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ATF System Applications
The ATF provides outstanding results in a variety of applications. However, each application might have different objectives and processing conditions.
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One key to ensuring the best results are obtained with the ATF™ System is to appreciate the differences involved with each application where it is used. Understanding what is important for each application and where the improvements in efficiency lie may mean a shift in focus for operating the ATF System.
Application Based Considerations:
- Different Cell Types : Insect cells and CHO cells have much common when grown in a bioreactor but also much separates them in how the ATF System can improve each individual process.
- Process Objectives : Obtaining a high cell concentration may not be the goal of a vaccine process - which cannot realize the benefit of more cells - but perhaps boosting virus numbers per cell is where the focus and effort for process improvement has the most impact.
- Expression Goals : A concentrated fed-batch approach may provide an excitingly high cell concentration but this may not translate to a similar protein production spike. Shortening the time however to produce an equivalent amount of protein could be significant while improving the turnaround time and total output of the research group. A high density cell bank made using the ATF System provides this.
Application Examples:
 Perfusion Learn how the ATF System eliminates common and troublesome problems such as cell damage and dead-zones. | Concentrated Fed-Batch A highly versatile process which permits great increases in cell and product concentrations as compared to Fed Batch processing. |
Cell Banking, Seed Expansion Learn how to streamline and simplify your cell banking & seed expansion steps with the ATF System. |
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732-460-0088, 732-460-0802 fax
732-460-0088, 732-460-0802 fax
